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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13408 | ZK824190 | Others , Serine Protease | |
ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA) as a potential treatment for multiple sclerosis(IC50s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively). | |||
T13257 | Upamostat | PAI-1 , Serine/threonin kinase , Serine Protease | |
Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor. | |||
T4317 | PF 429242 | NPC1L1 , Lipid | |
PF-429242 is a competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM). It is selective for site 1 protease against a panel of serine proteases. PF-429242 inhibits rat... | |||
T6190 | Telaprevir | VX-950,LY-570310,Incivek,MP-424 | HCV Protease , SARS-CoV |
Telaprevir (Incivek) (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM). | |||
T3226 | Paritaprevir free base | ABT-450,Veruprevir | HCV Protease |
Paritaprevir free base(ABT-450) is an orally bioavailable, synthetic acylsulfonamide inhibitor of the hepatitis C virus (HCV) protease complex comprised of non-structural protein 3 and 4A (NS3/NS4A), with potential acti... | |||
T10082 | DPP-IV-IN-1 | Others | |
DPP-IV-IN-1 is an effective inhibitor of dipeptidyl peptidase IV (DPP-IV), a serine protease (IC50: 4.6 nM). | |||
T76157 | Chymotrypsinogen | ||
Chymotrypsinogen is an inactive precursor of Chymotrypsin . Chymotrypsin is a serine protease produced by the pancreas [1] [2] . | |||
TP1628 | Activated Protein C (390-404), human | ||
Activated Protein C (390-404), human, a peptide derived from the vitamin K-dependent serine protease, effectively suppresses the anticoagulant activity of APC[1]. | |||
T74576 | Manusiran | ||
Manusiran is a potent TMPRSS6 (transmembrane protease serine 6) synthesis reducer [1] . | |||
T76202 | Recombinant Proteinase K | ||
Recombinant Proteinase K, a serine protease, targets the carboxy-terminal peptide bonds of both aliphatic and aromatic amino acids. It is utilized to digest proteins and eradicate contamination in nucleic acid preparatio... | |||
T14555 | BI-1230 | HCV Protease | |
BI-1230 is a potent inhibitor of HCV NS3 protease, exhibiting efficacy in the low nanomolar range, and notably suppresses viral replication. This compound demonstrates high selectivity, distinguishing effectively between... | |||
T76489 | Fluorescent Substrate for Subtillsin | ||
Subtilisin, a bacterial serine protease [1] [2], can be detected through the activity of a fluorescent substrate designed specifically for subtilisin. | |||
T73701 | Urokinase (peptidolytic) | ||
Urokinase peptidolytic (Urokinase-type plasminogen activator) is a serine protease, an inactive form (zymogen) of the serine protease plasminogen. Activation of plasmin triggers a proteolytic cascade reaction, which in t... | |||
T11269 | FD-IN-1 | Others | |
FD-IN-1 is a factor D (FD) inhibitor with an IC50 of 12 nM.FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5μM, respectively. Complement FD, a highly specific S1 serine protease, plays a... | |||
T80094 | Dansyl-Glu-Gly-Arg-Chloromethylketone | ||
Dansyl-Glu-Gly-Arg-Chloromethylketone is a protease inhibitor that specifically impedes serine/threonine proteases and has been shown to inhibit activated porcine factor IX [1]. | |||
TP1656 | VIR-165 | ||
VIR-165 is a modified form of virus inhibitory peptide (VIRIP), which corresponds to residues 353 to 372 of C-proximal region of human alpha1-antitrypsin, the most abundant circulating serine protease inhibitor. VIRIP in... | |||
T78354 | Subtilisin | EC 3.4.21.14 | |
Subtilisin, also known as rubinase, is a serine protease of bacterial origin. This enzyme exhibits thermal stability, pH tolerance, and calcium-dependent stability, characteristics that make it suitable for use as an add... | |||
T80059 | Complement factor I | Endogenous Metabolite | |
Complement factor I, a serine protease, attenuates complement activity both in the fluid phase and on cell surfaces, working alongside cofactors such as factor H (FH), complement receptor 1 (CR1/CD35), C4 binding protein... | |||
T75394 | Picornain 3C | ||
Picornain 3C, a protease present in picornaviruses, exhibits endopeptidase activity by specifically cleaving Gln-Gly bonds within the poliovirus polyprotein and, through substitution, cleaves Glu for Gln, and Ser or Thr ... | |||
T38052 | CRA-2059 TFA | ||
CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2]. Tryptase is a trypsin-like serine protease found as a major protein component in human ma... | |||
T38051 | CRA-2059 hydrochloride | ||
CRA-2059 hydrochloride is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2]. Tryptase is a trypsin-like serine protease found as a major protein compone... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T75648 | Rivulariapeptolides 1155 | ||
Rivulariapeptolides 1155 is a potent serine protease inhibitor, exhibiting inhibitory concentrations (IC50s) of 41.84 nM, 4.94 nM, and 56.54 nM against chymotrypsin, elastase, and proteinase K, respectively [1]. | |||
T75649 | Rivulariapeptolides 1185 | ||
Rivulariapeptolides 1185, a highly potent and selective serine protease inhibitor, exhibits IC50 values of 13.17 nM for chymotrypsin, 23.59 nM for elastase, and 55.26 nM for proteinase K [1]. | |||
T75652 | Molassamide B | ||
Molassamide B, a serine protease inhibitor, exhibits potent inhibitory activity, as evidenced by its IC50 values of 24.65 nM against chymotrypsin, 11.69 nM against elastase, and 5.42 nM against proteinase K [1]. | |||
T75651 | Rivulariapeptolides 988 | ||
Rivulariapeptolides 988 demonstrates significant potency and selectivity as a serine protease inhibitor, exhibiting IC50 values of 95.46 nM for chymotrypsin, 15.29 nM for elastase, and 85.50 nM for proteinase K [1]. | |||
T75650 | Rivulariapeptolides 1121 | ||
Rivulariapeptolides 1121 is a potent and selective serine protease inhibitor, demonstrating IC50 values of 35.52 nM for chymotrypsin, 13.24 nM for elastase, and 48.05 nM for proteinase K [1]. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00905 | Prostasin/PRSS8 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Prostasin/PRSS8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.8 kDa and the accession number is Q16651-1. | |||
TMPJ-00452 | Serpin A1a Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Serpin A1a is also known as alpha-1-antitrypsin, is a member of the serpin superfamily of serine proteinase inhibitors that are involved in the regulation of a number of proteolytic processes. Its primary target is elast... | |||
TMPJ-01069 | Serpin A1e Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Alpha-1-antitrypsin 1-5(SERPIN A1) is a secreted protein and belongs to the serpin family. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-... | |||
TMPJ-00980 | Complement Factor MASP3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway. The MBL pathway is initiated by the binding of MBL to specific carbohydrate structures found on the surface of a variety of micro... | |||
TMPY-02783 | Prostasin/PRSS8 Protein, Mouse, Recombinant (aa 30-289, His) | Mouse | Baculovirus Insect Cells |
Prostasin/PRSS8 Protein, Mouse, Recombinant (aa 30-289, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 29.3 kDa and the accession number is EDL17608.1. | |||
TMPJ-00468 | KLK10 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
KLK10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 34 KDa and the accession number is AAH02710.1. | |||
TMPJ-01083 | Serpin E2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Serpin E2 is a member of the Serpin superfamily. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuronlike cells. Its over-expression in mice lea... | |||
TMPJ-00733 | SPINK1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Serine Protease Inhibitor Kazal-Type 1 (SPINK1) is a trypsin inhibitor that prevent the trypsin-catalyzed premature activation of zymogens within the pancreas. Defects in SPINK1 are a cause of pancreatitis (PCTT). A dise... | |||
TMPH-03243 | Anionic trypsin-1 Protein, Rat, Recombinant (His) | Rat | P. pastoris (Yeast) |
N/A. Anionic trypsin-1 Protein, Rat, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 23.1 kDa and the accession number is P00762. | |||
TMPH-03242 | Anionic trypsin-1 Protein, Rat, Recombinant (E. coli, His) | Rat | E. coli |
N/A. Anionic trypsin-1 Protein, Rat, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 27.2 kDa and the accession number is P00762. | |||
TMPH-00484 | Cationic trypsin Protein, Canine, Recombinant (His & SUMO) | Canine | E. coli |
Cationic trypsin Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPJ-01204 | TPSAB1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(T... | |||
TMPJ-00375 | HGF Protein, Human, Recombinant (His) | Human | HEK293 Cells |
HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases and contains 4 kringle domains, 1 PAN domain and 1 peptidase S1 domain. HGF is secreted as an inactive 728 amino acid (aa) single chain propepti... | |||
TMPY-01589 | Serpin B10 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesi... | |||
TMPJ-01032 | SPINK7 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Serine protease inhibitor Kazal-type 7(SPINK7) is a secreted protein, that in humans is encoded by the SPINK7 gene. SPINK7 contains 1 Kazal-like domain. SPINK7 is probably serine protease inhibitor. Recombinant human SPI... | |||
TMPY-01900 | Kallikrein 4/KLK4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Kallikrein-4, also known as Enamel matrix serine proteinase 1, Kallikrein-like protein 1, KLK-L1, Serine protease 17, KLK4, PRSS17, and EMSP1, is a secreted protein that belongs to the peptidase S1 family and Kallikrein ... | |||
TMPY-01855 | Serpin A10 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Protein Z-dependent protease inhibitor, also known as PZ-dependent protease inhibitor, SERPINA1 and ZPI, is a secreted protein that belongs to the serpin family. It is expressed by the liver and secreted in plasma. SERPI... | |||
TMPK-00194 | TFPI Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and... | |||
TMPK-00923 | FAP Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital i... | |||
TMPY-01841 | Serpin I2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, infl... | |||
TMPK-00195 | TFPI Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and... | |||
TMPK-00373 | FAP Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital i... | |||
TMPY-01363 | Serpin A11 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesi... | |||
TMPK-01303 | TPSAB1 protein, Cynomolgus, Recombinant (His) | Cynomolgus | E. coli |
TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsinlike activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this... | |||
TMPK-00274 | PLAU/uPA Protein (active form), Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro... | |||
TMPY-01632 | Serpin B4 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesi... | |||
TMPJ-00625 | Serpin E1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Plasminogen activator inhibitor-1 (serpin E1) is a serine protease inhibitor which belongs to the serpin family. Serpin E1 acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. I... | |||
TMPK-00755 | Complement Factor D/CFD Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli sugge... | |||
TMPK-00671 | Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His) | Rhesus | HEK293 Cells |
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli sugge... | |||
TMPK-00151 | Complement Factor D/CFD Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli sugge... | |||
TMPJ-00881 | CTRB1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Chymotrypsinogen B (CTRB1) is a 263 amino acid protein with signal peptide (1-18) and Chymotrypsinogen B (19-263). Chymotrypsinogen B have three chains:Chymotrypsin B chain A(19-31), Chymotrypsin B chain B(34-164), Chymo... | |||
TMPY-01580 | PRSS2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Trypsin-2, also known as Trypsin II, Anionic trypsinogen, Serine protease 2, PRSS2 and TRY2, is a secreted protein that belongs to the trypsin serine protease family including Trypsin, PRSS1, PRSS2 and PRSS3. It consists... | |||
TMPY-01854 | DPP10 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Inactive dipeptidyl peptidase 1, also known as Dipeptidyl peptidase IV-related protein 3, Dipeptidyl peptidase X, Dipeptidyl peptidase-like protein 2, DPRP-3, DPL2 and DPP1, is a single-pass type II membrane protein w... | |||
TMPY-01814 | GASP-1/WFIKKN2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 2, also known as Growth and differentiation factor-associated serum protein 1, WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing-relat... | |||
TMPJ-00891 | Kallikrein 2/KLK2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave ... | |||
TMPY-01303 | Serpin A3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a plasma alpha globulin glycoprotein, and is a member of serpin superfamily of the serine protease inhibitors consisting of at least 35 members. SerpinA3 has be... | |||
TMPY-00821 | HGFA Protein (pro form), Human, Recombinant (His) | Human | HEK293 Cells |
HGF activator (HGFA) is a serum-derived serine protease and belongs to the peptidase family S1.HGFA is responsible for the conversion of hepatocyte growth factor (HGF), from the inactive single-chain precursor to the act... | |||
TMPH-02236 | TMPRSS2 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-... | |||
TMPH-02237 | TMPRSS2 Protein, Human, Recombinant (His & Myc) | Human | HEK293 Cells |
Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-... | |||
TMPY-02712 | Serpin B3 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
SERPINB3, also known as SCCA-1, belongs to the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was orig... | |||
TMPY-01711 | Serpin B2 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, infl... | |||
TMPY-01027 | Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Mast Cell Protease 1 (MMCP-1), also known as MCP-1, MCPT-1 and β-chymase, is a member of the Chymase family of chymotrypsin-like serine proteases. MCPT-1 is a 26 kDa β-chymase that is a component of mast cell granules. I... | |||
TMPY-04451 | AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&... | |||
TMPY-03745 | CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) | Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1. | |||
TMPY-03878 | Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) | Human | HEK293 Cells |
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1. | |||
TMPY-02501 | CD3D & CD3E Heterodimer Protein, Human, Recombinant | Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1. | |||
TMPY-02335 | OSMR Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
OSMR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 83.7 kDa and the accession number is O70458-1. | |||
TMPY-02112 | FGFR4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
FGFR4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22455-1. | |||
TMPY-01920 | BAFF/TNFSF13B Protein, Human, Recombinant (HEK293) | Human | HEK293 Cells |
BAFF/TNFSF13B Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 17 kDa and the accession number is Q9Y275-1. | |||
TMPY-02591 | SDF-1 Protein, Human, Recombinant | Human | E. coli |
SDF-1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.6 kDa and the accession number is P48061-1. | |||
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